CARDIORESPIRATORY SYSTEM MODELING IN PATIENTS INTOXICATED WITH ORGANOPHOSPHORUS COMPOUNDS
Palabras clave:
mechanical ventilation, sympathetic system, parasympathetic systemResumen
The management of toxicity by poisoning with organophosphorus compounds is difficult for medical personnel due to the lack of knowledge about the clinical feature evolution and the low percentage of therapeutic efficiency used, which leads to patients to require long and expensive recovery periods in an intensive care unit. In the current work, an extended cardiorespiratory model considering the respiratory muscle activity was proposed to improve the determining of the appropriate timing for initiating extubation maneuvers in patients intoxicated with organophosphorus compounds. This opens the possibility of exploring and using surface electromyography as tool for understanding the cardiorespiratory response in these patients. According to the experimental data and optimization results, this muscular response is correlated with the parasympathetic-sympathetic action measured through the heart rate. This can be very important in diagnosis of health and disease states. Having more knowledge about the balance of these systems allows evaluating the efficiency of pharmacological treatment, given the clinical condition of the intoxicated patient
Biografía del autor/a
María Bernarda Salazar Sánchez, Universidad de Antioquia
Citas
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